Director, Brand Communications

About the position

Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, Lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. As we prepare for our first commercial launch, we are seeking an experienced brand communications leader who is energized by the opportunity to build from the ground up, establish the disease and brand narrative, and shape the PR and communications ecosystem for a best-in-class launch. Reporting to the VP of Marketing, the Director, Brand Communications will be the single point of accountability for all brand PR and communications at Mineralys. This is a new role built for someone who thrives in pre-launch environments and is energized by building from the ground up — owning the narrative for Lorundrostat across HCPs, patients, advocacy organizations, and the media from pre-launch through commercialization. The role requires both strategic and executional leadership, spanning brand PR agency management, disease awareness and market shaping, advocacy and ambassador programs, and congress and launch communications. Mineralys has an established corporate communications function that owns enterprise reputation and investor relations — this role is focused entirely on brand and disease communications and requires a genuine collaborative partner mindset with that team. A strong partnership with Corporate Communications is critical to ensure alignment reinforced through a dotted-line reporting relationship to the SVP of Corporate Communications.

Responsibilities

• Own the development and execution of Brand Communications strategy, including disease awareness, market shaping, and launch narrative across HCP, patient, advocacy, media, and scientific audiences
• Develop and govern the content calendar for Brand PR, ensuring message consistency, channel sequencing, and compliance across earned and owned channels
• Own paid amplification strategy for earned content, including boosting of media coverage, publication announcements, and disease education assets within pre-approved legal and regulatory frameworks
• Lead product-specific media strategy and launch communications planning, including key milestones, narrative arcs, and channel sequencing in coordination with Brand, Corporate Communications, and Medical teams
• Partner with commercial, digital, and brand teams to ensure consistent narrative translation across paid, owned, and earned channels
• Drive disease-state education and awareness programs, including unmet-need storytelling and pre-launch market seeding across HCP and patient audiences
• Own congress and data communications strategy, including partnership on press release development, on-site media engagement, KOL interview logistics, and post-congress amplification
• Partner on the KOL and DOL engagement strategy and integration of clinical voice into PR planning
• Partner with Medical Affairs and Brand Marketing to build and execute advocacy partnerships across cardiology, hypertension, primary care, and health-equity organizations, designing original co-created initiatives beyond transactional sponsorships
• Develop and execute celebrity and patient ambassador programs, including identification, vetting, onboarding, content development, channel planning, speaker preparation, and MLR/PRC compliance guardrails
• Develop and execute patient story programs tied to the disease experience, including identification of storytelling opportunities, content development, speaker preparation, channel planning, and compliance guardrails
• Own brand and disease-state social media strategy and content calendar, coordinating with Digital and MarTech on channel planning, content amplification, and reuse across approved channels
• Build and operate a real-time flag-and-act capability for brand-relevant media, social, advocacy, and competitive moments, including monitoring, tiered escalation, internal routing, and rapid approval protocols
• Develop issue-preparedness infrastructure, including scenario planning, pre-approved holding statements, and response protocols in coordination with Legal and Corporate Communications, with alignment to corporate issues-management protocols
• Lead and manage the Brand PR agency end-to-end, including, day-to-day direction, briefing, feedback, budget oversight, performance management, and quarterly planning
• Serve as the primary bridge between Brand Marketing, Corporate Communications, Medical Affairs, Legal, Regulatory, Investor Relations, and external agency partners on all communications matters
• Actively participate in MLR/PRC, bringing Brand PR materials through review efficiently, with strong version control, clear approvals, and minimal rework
• Measure message pull-through, quality of coverage, share of voice, engagement, advocacy progress, and recommendations for optimization
• Manage the Brand Communications budget and relevant external vendor and agency relationships

Requirements

• MBA or bachelor’s degree plus 10+ years of pharmaceutical, biotech, or healthcare communications experience, with at least 6 years in brand PR or communications in an HCP or patient-facing context
• Demonstrated ownership of brand communications strategy in a regulated pharmaceutical or biotech environment
• Track record of managing and holding agencies accountable in an MLR/PRC-governed environment
• Experience building or scaling an advocacy engagement program, with knowledge of the cardiology and hypertension association landscape preferred
• Familiarity with celebrity or patient ambassador program development, including compliance and legal frameworks
• Deep fluency with MLR/PRC processes and demonstrated ability to move efficiently through review without sacrificing quality
• A builder mindset with high personal accountability, resourcefulness, and a collaborative spirit
• Proven ability to lead through ambiguity and define direction in a fast-moving, pre-launch environment
• Strong cross-functional leadership and the ability to influence without authority
• Excellent writing, messaging, and communication skills

Nice-to-haves

• Cardiovascular and/or launch experience is strongly preferred

Benefits

• This position requires up to 20% travel. Frequently travel is outside the local area and overnight. Some of the travel may be international.